Fig. 6
From: Single-cell sequencing analysis of peripheral blood in patients with moyamoya disease
Pseudo-time series analysis. (A) Darker blue indicates early cell differentiation, from dark blue to light blue. (B) The cells have a total of seven differentiated states. (C, D) NK cells differentiated early, corresponding to state 1, corresponding to two major clusters (E) The differentiation states of the two Moyamoya disease samples were consistent. (F) The expression of 8 of the 11 key genes was changed. Among them, the expressions of CSTB, LGALS3 and IFI6 genes were firstly increased and then decreased, the expressions of GOLGA2 and NDRG1 were firstly decreased and then increased, and the expressions of SPINT2, LGALS3BP and PTP4A1 were gradually increased