Morphometric measurements of intraoral anatomy in children with Beckwith-Wiedemann syndrome: a novel approach

Table 3 Outcome variance between surgery and non-surgery cohorts

	History of Tongue Reduction Surgery
	No	Yes	p
BWS Clinical Score	4.79 ± 4.31	9.21 ± 2.80	*0.009
Percent Mosaicism	64 ± 8%	57 ± 15%	0.210
BIG Score	0.50 ± 0.67	1.86 ± 0.53	*<0.001
AHI	6.59 ± 3.80	4.07 ± 4.62	0.232
SpO₂	0.87 ± 0.05	0.85 ± 0.06	0.411
Ridging Grade	0.62 ± 0.61	1.37 ± 0.76	*0.008
Tonsil Grade	1.78 ± 1.39	1.00 ± 1.15	0.268
Lateral Wall Grade	2.00 ± 0.47	2.33 ± 0.52	0.411
OMNP
Mallampati	1.75 ± 0.50	2.00 ± 0.82	0.549
Scale	288.2 ± 57.97	278.7 ± 82.94	0.674
MArea	3.120E + 6 ± 7.081E + 6	1.097E + 6 ± 5.831E + 5	0.315
MWidth	1242 ± 494.8	1208 ± 386	0.816
MHeight	1162 ± 506.3	1212 ± 494.8	0.775
TWidth	1064 ± 319.7	1064 ± 397.4	1
TEMA
Mallampati	2.10 ± 0.32	2.00 ± 0.63	0.359
Scale	272.2 ± 62.8	267.2 ± 93.48	0.82
MWidth	1190 ± 275.8	1213 ± 403.9	0.817
TArea	1.090E + 6 ± 3.907E + 5	1.154E + 6 ± 7.253E + 5	0.754
TWidth	1018 ± 235.6	1141 ± 399.4	0.175
TLength	1255 ± 330.3	1131 ± 469.7	0.431
TEML
Scale	270.7 ± 43.09	251.2 ± 62.09	0.335
TArea	5.252E + 5 ± 1.470E + 5	4.104E + 5 ± 1.983E + 5	0.096
TCurve	1621 ± 259	1320 ± 320	*0.014
TLength	1232 ± 168	1062 ± 407.8	0.144
TThick	518.6 ± 125.1	485.6 ± 131.3	0.511

AHI: apnea-hypopnea index, SpO₂: oxygen saturation nadir, BWS: Beckwith-Wiedemann Syndrome, BIG: BWS Index of macroGlossia, OMNP: open mouth no phonation, TEMA: tongue extended maximally anterior, TEML: tongue extended maximally lateral
All values reported as mean ± standard deviation
p-values corresponding to two-sampled student’s t-tests are noted in italicized text.
p-values corresponding to chi-squared tests are noted in underlined text.
*indicates p-values that remain statistically significant following Benjamini-Hochberg correction with a false discovery rate of < 0.25

ISSN: 1750-1172