| TS1 Gly406Arg yes/total (%) n = 30 | TS2 Gly406Arg yes/total (%) n = 11 | Gly402Ser yes/total (%) n = 6 | Diagnosed nsLQT8 yes/total (%) n = 12 | Other yes/total (%) n = 28 | Correlation p-value |
---|---|---|---|---|---|---|
Neurodevelopmental concerns Sspeech concerns | 18/30 (60) 18/26 (69) | 6/10 (60) 6/9 (67) | 5/6 (83) 5/6 (83) | 4/11 (36) 4/10 (40) | 23/27 (85) 17/18 (94) | 0.0314 0.0257 |
 Speech delay | 18/26 (69) | 6/9 (67) | 2/6 (33) | 3/10 (30) | 15/17 (88) |  |
 Receptive delay | 10/20 (50) | 5/7 (71) | 2/6 (33) | --- | 5/17 (29) |  |
 Expressive delay | 13/20 (65) | 5/7 (71) | 2/6 (33) | 2/4 (50) | 12/17 (71) |  |
 Odd sounds | 5/25 (20) | 2/8 (25) | 2/6 (33) | 1/4 (25) | 9/17 (53) |  |
Educational | Â | Â | Â | Â | Â | Â |
 Global developmental delay | 0/30 (0) | 2/10 (20) | 0/6 (0) | --- | 4/5 (80) |  |
 Knows alphabet | 13/17 (76) | 1/4 (25) | 6/6 (100) | 12/12 (100) | 9/20 (45) |  |
 Age when spoke full sentences (yrs) | 2.5–5 | 2.5–7 | 1–4 | 0–3.5 | 1.5–6 |  |
 At grade level  Learning concerns: | 5/17 (29) 11/16 (69) | 0/5 (0) 4/4 (100) | 0/1 (0) 4/6 (67) | 9/11 (82) 4/9 (44) | 3/15 (20) 12/15 (80) |  |
  Problems reading | 12/16 (75) | 1/4 (25) | 3/6 (50) | 2/9 (22) | 12/15 (80) |  |
  Problems with numbers | 10/15 (67) | 4/4 (100) | 3/6 (50) | 4/9 (44) | 10/15 (67) |  |
 Accurate memory | 8/18 (44) | 1/4 (25) | 1/4 (25) | 2/9 (22) | 2/15 (13) |  |
 Delayed potty training (> 4yrs) | 10/20 (50) | 7/8 (86) | 2/4 (50) | 2/7 (29) | 2/7 (29) |  |
 Delayed night training (> 5yrs) | 7/17 (41) | 7/7 (100) | 1/4 (25) | 4/10 (40) | --- |  |
Social ability | Â | Â | Â | Â | Â | Â |
 Not tested | 13/19 (68) | 1/5 (20) | 3/6 (22) | --- | --- |  |
 Autism | 6/12 (50) | 4/9 (44) | 1/3 (33) | 2/8 (25) | 8/14 (57) | 0.6873 |
 ADD/ADHD | 5/11 (45) | 5/9 (56) | 3/5 (60) | 1/8 (13) | 4/14 (29) | 0.2840 |
 Shy/anxious | 14/24 (58) | 4/7 (57) | 5/6 (83) | 2/10 (2) | 7/19 (37) |  |
 Odd behaviors | 13/23 (57) | 4/5 (80) | 1/4 (25) | 2/10 (2) | 6/19 (32) |  |
 Plays with age group | 12/23 (52) | 2/4 (50) | 1/4 (25) | 6/10 (60) | 8/19 (42) |  |
 Prefers being alone | 11/21 (52) | 2/4 (50) | 2/6 (33) | 5/10 (50) | 6/19 (32) |  |
 Prefers quiet environment | 14/21 (67) | 3/5 (60) | 2/6 (33) | 3/10 (30) | 7/19 (37) |  |
 Prefers animals | 8/19 (42) | 1/5 (25) | 0/6 (0) | 3/10 (30) | 4/19 (21) |  |
Other neural development | 18/24 (75) | 6/9 (67) | 6/6 (100) | 8/11 (73) | 15/22 (68) | 0.6462 |
 Routine oriented | 17/22 (77) | 5/5 (100) | 4/6 (67) | 5/10 (50) | 9/19 (47) |  |
 Orders objects | 9/23 (39) | 1/3 (33) | 1/4 (25) |  | 6/19 (32) |  |
 Seizure disorder | 10/30 (33) | 5/7 (71) | 0/6 (0) | 1/11 (9) | 11/22 (50) |  |
 Has phobias | 9/24 (38) | 0/4 (0) | 0/6 (0) | 2/8 (25) | 1/14 (7) |  |
 Anger/violence | 11/23 (48) | 2/5 (40) | 2/6 (33) | 1/8 (13) | 4/14 (29) |  |
 Depression | 1/6 (17) | --- | 0/6 (0) | 2/8 (25) | 2/14 (14) |  |
 OCD | 4/19 (21) | --- | 1/6 (17) | 2/8 (25) | 3/14 (21) |  |
 Schizophrenia | 1/19 (5) | --- | 1/6 (17) | 0/8 (0) | 0/14 (0) |  |
 Severe headaches | 2/10 (11) | 0/2 (0) | 2/6 (33) | 1/8 (13) | 1/14 (7) |  |
Adult life skills | Â | Â | Â | Â | Â | Â |
 Rides bus alone | 2/6 (33) | --- | --- | 6/6 (100) | --- |  |
 Has driver’s license | 1/6 (17) | --- | --- | 6/6 (100) | --- |  |
 Makes monetary change | 1/6 (17) | --- | --- | 6/6 (100) | --- |  |