Fig. 6
From: A therapeutic approach to pantothenate kinase associated neurodegeneration: a pilot study
Effect of pantothenate, pantethine, omega-3 and vitamin E supplementation on PDH activity. Control and PKAN fibroblasts (P1, P2, P3) were treated with 5 µM pantothenate, 5 µM pantethine, 5 µM vitamin E and 5 µM omega 3 for 10 days (+ T). (A) PDH activity in whole cellular extracts was measured as described in Material and Methods. (B) Quantification of PDH activity. Data represent the mean ± SD of three separate experiments. *p < 0.01 between PKAN patients and controls; aap < 0.01 between untreated and treated cells