The healthcare burden of pulmonary alveolar proteinosis (PAP)

Table 1 Baseline characteristics

Patient demographics	PAP cohort (N = 2312)		Matched control cohort (N = 9247)		P value
Patient demographics	N	%	N	%	P value
Age					0.99705
Mean (SD)	61	17.75	61	17.75
Gender					0.99745
Male	740	32	2960	32
Female	1572	68	6287	68
Patient race & ethnicity
White (non-hispanic)	1461	63	5839	63
White (hispanic)	211	9	743	8
Black or African American	139	6	435	5
Asian	42	2	195	2
American Indian or Alaska Native	0	0	0	0
Native Hawaiian or Other Pacific Islander	5	0	22	0
Unknown Race	454	20	2013	22
Patient payer coverage
Commercial	759	33	2636	29	< 0.001
FFS medicaid	110	5	280	3	< 0.001
Managed medicaid	348	15	587	6	< 0.001
Medicare	831	36	2114	23	< 0.001
Other payer	46	2	295	3	< 0.005
Unknown payer	218	9	3335	36	< 0.001
Charlson comorbidity index, n (%)
Score, mean (SD)	1.44	1.96	0.41	1.11
COPD	726	31	713	8	< 0.001
Diabetes	477	21	811	9	< 0.001
Renal disease	296	13	403	4	< 0.001
Congestive heart failure	307	13	304	3	< 0.001
Diabetes with complications	275	12	377	4	< 0.001
Non-metastatic malignancies	264	11	457	5	< 0.001
Peripheral vascular disease	253	11	311	3	< 0.001
Cerebrovascular disease	187	8	273	3	< 0.001
Mild liver disease	165	7	174	2	< 0.001
Rheumatologic disease	134	6	118	1	< 0.001
Myocardial infarction	86	4	113	1	< 0.001
Dementia	46	2	134	1	< 0.05
Metastatic solid tumor	40	2	60	1	< 0.001
Hemiplegia paraplegia	34	1	21	0	< 0.001
Peptic ulcer disease	27	1	38	0	< 0.001
AIDS	23	1	18	0	< 0.001
Moderate or severe liver disease	8	0	16	0	< 0.05

ISSN: 1750-1172