Fig. 4

Lower extremity function progression. A scatter plot was created to illustrate the correlations between (a) age and (b) disease duration relative to the total reported raw score for lower extremity function. The solid lines indicate progression within a singular participant over time for data with multiple submissions whereas the dashed lines indicate overall progression in males (blue) and females (pink) using the latest submission. Both male (blue squares) and female participants (pink circles) showed a rapid decline in their overall mobility with increasing age and disease duration