Fig. 5

Cognitive function progression. A scatter plot was created to illustrate the correlations between (a) age and (b) disease duration relative to the total reported raw score for cognitive function. The solid lines indicate progression within a singular participant over time for data with multiple submissions whereas the dashed lines indicate overall progression in males (blue) and females (pink) using the latest submitted value. Both male (blue squares) and female participants (pink circles) showed a decline in their overall cognitive abilities with increasing age whereas little to no decline with increasing disease duration