Table 2 Cumulative incidence and 95% CI of patients achieving the MSD of the total PDMS-2 score and each motor milestone
Month 0 | Month 6 | Month 12 | Month 18 | Month 24 | Month 30 | Month 36 | Month 42 | Month 48 | Month 54 | Month 60 | Month 66 | Month 72 | Month 78 | Month 84 | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
40pts PDMS-2 change | 0 (0, 0) | 50 (28, 65) | 75 (53, 87) | 86 (65, 94) | 86 (65, 94) | 90 (68, 97) | 90 (68, 97) | 95 (70, 99) | 100 (70, 99) | 100 (70, 99) | 100 (70, 99) | 100 (70, 99) | 100 (70, 99) | 100 (70, 99) | 100 (70, 99) |
Head control | 0 (0, 0) | 17 (2.2, 29) | 52 (30, 67) | 71 (48, 83) | 75 (52, 87) | 75 (52, 87) | 87 (65, 96) | 87 (65, 96) | 87 (65, 96) | 87 (65, 96) | 87 (65, 96) | 87 (65, 96) | 87 (65, 96) | 87 (65, 96) | 87 (65, 96) |
Sitting unassisted | 0 (0, 0) | 3.3 (0, 9.5) | 25 (7.0, 39) | 40 (18, 56) | 56 (32, 71) | 68 (44, 82) | 68 (44, 82) | 72 (48, 85) | 77 (52, 89) | 82 (56, 93) | 82 (56, 93) | 82 (56, 93) | 82 (56, 93) | 82 (56, 93) | 82 (56, 93) |
Standing with support | 0 (0, 0) | 3.3 (0, 9.5) | 6.8 (0, 15) | 11 (0, 21) | 27 (7.5, 42) | 31 (10, 47) | 36 (14, 52) | 44 (20, 61) | 44 (20, 61) | 44 (20, 61) | 49 (24, 66) | 49 (24, 66) | 58 (28, 75) | 58 (28, 75) | 58 (28, 75) |
Walking with assistance | 0 (0, 0) | 0 (0, 0) | 0 (0, 0) | 0 (0, 0) | 4.2 (0, 12) | 8.7 (0, 20) | 14 (0, 27) | 14 (0, 27) | 14 (0, 27) | 24 (3.0, 41) | 24 (3.0, 41) | 24 (3.0, 41) | 24 (3.0, 41) | 24 (3.0, 41) | 24 (3.0, 41) |