Table 1 Inclusion and exclusion criteria for qualitative and HRQOL studies
Include | Exclude |
|---|---|
Patient population include adults (i.e., age ≥ 18 years) | Population includes children and/or adolescents (i.e., age < 18 years) |
Report a study of people who have AATD and lung disease that includes qualitative appraisal of patient experiences with the condition or its treatment | Editorials, clinical practice guidelines, commentary |
Report a clinical or observational study focused on assessing HRQOL in people with AATD (with or without a lung-related diagnosis) using a self-reported outcome measure | Human cell or genetic studies, population prevalence studies with no reporting of symptoms or impacts of AATD, single case studies, or other studies not relevant to the review aims (i.e., do not include substantive information about patient-centered outcomes) |
Studies not specifically focused on patients with AATD or focused only on patients with AATD and other disease exacerbations (e.g., liver or cardiac disease) | |
Systematic reviews of objective outcomes, such as blood tests or tests of lung capacity |