Table 1 Descriptive table of the study population

Gender (M)

16

Median age ± σ (years; min–max)

10.5 ± 3.42 (6.2–16.6)

Gene (number of children)

COL1A1

20

COL1A2

7

IFITM5

1

THEM38B

1

Not detected

1

Disease type (number of children), based on genetic variant

Moderate familial

25

Severe familial

1

Moderate de Novo

3

Severe de Novo

1

Bisphosphonates before M0 (number of children)

17

Fractures (number of children)

Within the 12 months before inclusion

12

Between M0-M12

6

Median weight Z-score

0.37

Range of weight Z-scores

−2.41 – 3.40

Median height Z-score

− 0.70

Range of height Z-scores

−6.94 – 3.85

Engagement in sport activities (number of children)

24

Outside school activities (number of children)

19