Operative treatment of severe scoliosis and pelvic obliquity in patients with spinal muscular atrophy: assessment of outcomes and complications

Sun, Heng; Huang, Yizhen; Dong, Yulei; Wang, Zhen; Zhao, Junduo; Huang, Xuan; Chen, Weiyun; Shen, Jianxiong

doi:10.1186/s13023-025-03682-8

Orphanet Journal of Rare Diseases

Table 2 Pulmonary function and motor status in patients with spinal muscular atrophy and severe scoliosis before and after scoliosis surgery

From: Operative treatment of severe scoliosis and pelvic obliquity in patients with spinal muscular atrophy: assessment of outcomes and complications

Case no	Sex	SMA type	Age of scoliosis onset (years)	Age of scoliosis surgery (years)	Follow-up duration (months)	Preoperative FVC(mL)	Postoperative FVC (mL, 6-months)	Postoperative FVC (mL, last follow-up)	Changes in FVC (last follow-up)	Preoperative motor status	Postoperative motor status (6-months)	Postoperative motor status (last follow-up)	Changes in motor status (last follow-up)
1	F	2	7	13	36	1210	1430	1400	Improved	Sit with support	Sit with support	Sit with support	Static
2	F	3	4	17	72	630	720	650	Improved	Independent sit	Independent sit	Independent sit	Static
3	F	2	7	17	43	520	480	510	Worsened	Sit with support	Independent sit	Independent sit	Improved
4	F	2	6	20	31	810	760	640	Worsened	Sit with support	Independent sit	Independent sit	Improved
5	M	2	9	13	30	2620	2480	2740	Improved	Sit with support	Independent sit	Independent sit	Improved
6	F	2	9	23	27	540	630	610	Improved	Sit with support	Independent sit	Independent sit	Improved
7	M	2	10	16	31	1260	1150	1060	Worsened	Sit with support	Sit with support	Sit with support	Static
8	F	2	4	12	43	1090	1140	1210	Improved	Independent sit	Independent sit	Independent sit	Static
9	F	2	8	11	38	640	530	570	Worsened	Sit with support	Independent sit	Independent sit	Improved
10	F	3	2	13	44	890	950	920	Improved	Sit with support	Independent sit	Independent sit	Improved
11	M	3	3	18	36	1250	1180	1040	Worsened	Sit with support	Sit with support	Sit with support	Improved
12	F	3	7	13	27	800	630	580	Worsened	Sit with support	Independent sit	Independent sit	Improved
13	F	3	6	20	31	1560	1320	1410	Worsened	Sit with support	Independent sit	Independent sit	Improved
14	F	3	9	13	24	1780	1840	1890	Improved	Sit with support	Sit with support	Sit with support	Static
15	M	2	5	12	42	880	960	980	Improved	Sit with support	Independent sit	Independent sit	Improved
16	F	2	9	17	42	820	780	850	Improved	Sit with support	Independent sit	Independent sit	Improved
17	F	2	6	11	32	720	860	970	Improved	Sit with support	Independent sit	Independent sit	Improved
18	M	3	15	22	56	2920	2780	2720	Worsened	Independent sit	Independent sit	Independent sit	Static
19	F	2	7	15	31	1510	1360	1630	Improved	Sit with support	Independent sit	Independent sit	Improved
20	M	2	8	15	66	880	740	550	Worsened	Sit with support	Independent sit	Independent sit	Improved
21	M	2	9	26	48	1960	1850	1720	Worsened	Sit with support	Independent sit	Independent sit	Improved
22	F	3	4	17	56	990	840	740	Worsened	Independent sit	Independent sit	Independent sit	Static

F, female; FVC, forced vital capacity; M, male; SMA, spinal muscular atrophy

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ISSN: 1750-1172

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