Fig. 5

A String-based PPI network with shared DEGs B Utilizing Cytoscape’s MCODE plug-in, the cluster subnet brings to light hub genes within the PPI network. Nodes and edges visually depict cluster members and their interconnections C The heatmap illustrates the correlation between central genes and the ratio of immune cells. Hub gene expression is depicted on the y-axis, while immune cells are represented on the x-axis. The positive correlation is indicated by red, the negative correlation by blue, and the intensity of color saturation reflects the strength of the correlation, as depicted in the accompanying barchart on the right