Table 1 Demographic characteristics and select comorbidities among the total Rtt population (n = 89)

Female

82

92.1%

Race

 Asian

1

1.1%

 Black

6

6.7%

 White

59

66.3%

 Unknown

23

25.8%

Aspiration

 Aspiration (known or suspected)

25

28.1%

 Non-aspiration

64

71.9%

Abnormal breathing and other respiratory conditions

 Asthma

11

12.4%

 Abnormal breathing

55

61.8%

 Choking**

21

23.6%

 Sleep apnea

29

32.6%

Behavioral and psychiatric comorbidities

 Anxiety

16

18.0%

 Behavior disorders (e.g., aggression)

16

18.0%

Cardiac comorbidities

 Cardiac arrhythmias

21

23.6%

 QT prolongation

12

13.5%

Gastrointestinal and nutritional comorbidities*

 Constipation

63

70.8%

 Dysphagia

46

51.7%

 Gastrostomy

27

30.3%

 GERD

40

44.9%

 Nutritional deficiency

39

43.8%

 Vomiting

36

40.4%

Musculoskeletal comorbidities

 Scoliosis

36

40.4%

 Kyphosis and other spinal deformities

21

23.6%

Neurologic comorbidities

 Epilepsy

65

73.0%

 Sleep dysfunction

32

36.0%

 Movement disorders

15

16.9%

 Weakness/Paralysis

32

36.0%

≥ 1 Inpatient admissions

 Aspiration-specific

8

9.0%

 LRTI-specific

10

14.6%

 Respiratory failure-specific

16

18.0%