Table 3 Association between SLC6A4 gene polymorphisms with CAD
MODEL | CAD PATIENTS (N = 400) | CONTROLS (N = 400) | OR (95% CI) | Adjusted p- value |
|---|---|---|---|---|
5-HTTLPR Dominant SL + LL vs. SS Recessive LL vs. SL + SS | 190/210 40/360 | 155/245 25/375 | 1.43 (1.08–1.89) 1.67 (0.99–2.80) | 0.02* 0.05 |
rs25531 Dominant S’LA+LALA vs. S’S’ Recessive LA vs. S’LA+ S’S’ | 124/276 17/383 | 112/288 15/385 | 1.16 (0.85–1.57) 1.14 (0.56–2.31) | 0.6 0.7 |
VNTR STin2 Dominant 12/10 + 10/10 vs. 12/12 Recessive 10/10 vs. 12/10 + 12/12 | 210/190 39/361 | 220/180 53/347 | 0.90 (0.68–1.19) 0.71 (0.46–1.10) | 0.5 0.2 |